Based on the provided information, pHix mature hops extract (MHE) compares favorably to other fat-reducing supplements in terms of effectiveness and safety: 1. Effectiveness: The table indicates that MHE has an effectiveness rating of 4.0 for fat reduction, which is among the highest ratings provided. This is supported by clinical research showing significant reductions in visceral fat area and total fat area in subjects taking MHE compared to a placebo group[1]. 2. Safety: Mature Hops Extract appears to have a relatively mild side effect profile, with common side effects including drowsiness and dizziness. The clinical study reported no adverse events related to MHE consumption[1]. 3. Mechanism: MHE promotes fat burning…